Term Name: pregabalin
Synonyms: (3S)-3-(aminomethyl)-5-methylhexanoic acid, (S)-3-Isobutyl GABA, 3-Isobutyl GABA, Lyrica, pregabalin
Definition: A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
Ontology: ChEBI [CHEBI:64356]  ( EBI )

Relationships
is a type of: gamma-amino acid
has_functional_parent: gamma-aminobutyric acid
has_role: anticonvulsant calcium channel blocker