Term Name: | pregabalin |
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Synonyms: | (3S)-3-(aminomethyl)-5-methylhexanoic acid, (S)-3-Isobutyl GABA, 3-Isobutyl GABA, Lyrica, pregabalin |
Definition: | A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. |
Ontology: | ChEBI [CHEBI:64356] ( EBI ) |