Term Name:	2-methyl-6-(phenylethynyl)pyridine hydrochloride
Synonyms:	2-methyl-6-(phenylethynyl)pyridine hydrochloride, 2-methyl-6-(phenylethynyl)pyridinium chloride, 6-methyl-2-(phenylethynyl)pyridine hydrochloride, 6-methyl-2-(phenylethynyl)pyridinium chloride, MPEP hydrochloride
Definition:	A hydrochloride salt obtained by reaction of 2-methyl-6-(phenylethynyl)pyridine with one equivalent of hydrochloric acid. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.
Ontology:	ChEBI [CHEBI:64158]  ( EBI )