Term Name: imetit
Synonyms: 2-(1H-imidazol-4-yl)ethyl carbamimidothioate, S-(2-(4-Imidazolyl)ethyl)isothiourea
Definition: An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
Ontology: ChEBI [CHEBI:64156]  ( EBI )

Relationships
is a type of: imidazoles imidothiocarbamic ester
has_role: H3-receptor agonist H4-receptor agonist
inverse is_conjugate_acid_of: imetit(2+)
is_conjugate_base_of: imetit(2+)