Term Name: etravirine
Synonyms: 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile, etravirine
Definition: An aminopyrimidine that consists of 2,6-diaminopyrimidine bearing a bromo substituent at position 5, a 4-cyano-2,6-dimethylphenoxy substituent at position 4 and having a 4-cyanophenyl substituent attached to the 2-amino group. NNRTI of HIV-1, binds directly to RT and blocks RNA-dependent and DNA-dependent DNA polymerase activities
Ontology: ChEBI [CHEBI:63589]  ( EBI )

Relationships
is a type of: aminopyrimidine aromatic ether dinitrile organobromine compound
has_role: antiviral agent HIV-1 reverse transcriptase inhibitor