Term Name: amorolfine
Synonyms: (+-)-cis-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine, (2R,6S)-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine, amorolfina, amorolfine, amorolfinum, meso-2,6-dimethyl-4-(2-methyl-3-(p-tert-pentylphenyl)propyl)morpholine, meso-2,6-dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine
Definition: A member of the class of morpholines that is cis-2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a racemic 2-methyl-3-[p-(2-methylbutan-2-yl)phenyl]propyl group. An inhibitor of the action of squalene monooxygenase, Delta(14) reductase and D7-D8 isomerase and an antifungal agent, it is used (generally as its hydrochloride salt) for the topical treatment of fungal nail and skin infections.
Ontology: ChEBI [CHEBI:599440]  ( EBI )

Relationships
is a type of: morpholine antifungal drug tertiary amino compound
has_role: EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor EC 1.14.13.132 (squalene monooxygenase) inhibitor EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor
inverse is_conjugate_acid_of: amorolfine(1+)
is_conjugate_base_of: amorolfine(1+)