Term Name: 2-hydroxy-4-methylvaleric acid
Synonyms: 2-hydroxy-4-methylpentanoic acid, 2-hydroxyisocaproic acid, 2-hydroxyisohexanoic acid, alpha-Hydroxyisocaproic acid, Leucic acid, leucinic acid
Definition: A valeric acid derivative having a hydroxy substituent at the 2-position and a methyl substituent at the 4-position; an alpha-hydroxy analogue of leucine. A bacterial metabolite, it has also been isolated from amniotic fluid, was found in a patient with dihydrolipoyl dehydrogenase deficiency and is present in the urine of patients with short bowel syndrome.
Ontology: ChEBI [CHEBI:59783]  ( EBI )

Relationships
is a type of: 2-hydroxy fatty acid branched-chain fatty acid
has subtype: (R)-2-hydroxy-4-methylpentanoic acid (S)-2-hydroxy-4-methylpentanoic acid
has_functional_parent: valeric acid
has_role: metabolite
inverse is_conjugate_base_of: 2-hydroxy-4-methylvalerate
is_conjugate_acid_of: 2-hydroxy-4-methylvalerate