Term Name: polymyxin
Synonyms: polymixin, polymycin, polymyxins
Definition: Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria.
Ontology: ChEBI [CHEBI:59062]  ( EBI )

Relationships
is a type of: heterodetic cyclic peptide lipopeptide
has subtype: colistimethate colistimethate A colistimethate B colistimethate sodium colistin colistin A colistin A sodium methanesulfonate colistin B colistin B sodium methanesulfonate polymyxin B1 polymyxin B2
has_role: antibacterial agent antimicrobial agent