Term Name: genotoxin
Synonyms: genotoxic agent, genotoxic agents, genotoxins
Definition: A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Ontology: ChEBI [CHEBI:50902]  ( EBI )

Relationships
is a type of: aetiopathogenetic role
has subtype: mutagen
inverse has_role: 1,5-dinitronaphthalene 1-methyl-3-octylimidazolium tetrafluoroborate 1-naphthol 1-penten-3-one 2,6-dinitrotoluene 2-naphthol 4-methoxyestrone 7-epi-cylindrospermopsin acridine arsenic trichloride benzamidoxime benzo[a]pyrene-7,8-dione beryllium dichloride cadmium nitrate cadmium nitrate tetrahydrate camptothecin carvacrol ether catechol cisplatin cobalt(2+) sulfate heptahydrate colibactin cylindrospermopsin ebselen estragole ethoxyquin ethyl methanesulfonate hydrogen peroxide hydrogen sulfide hydroxyurea imidacloprid MeIQx methyl methanesulfonate N-(2,6-diethylphenyl)-2-chloroacetamide N-ethyl-N-nitrosourea N-hydroxy-MeIQx N-hydroxy-PhIP o-anisidine oxoplatinum p-anisidine parathion-methyl paxilline pillar[5]arene riddelliine riddelliine N-oxide tolylfluanid