Term Name: prodrug
Synonyms: Prodrugs
Definition: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Ontology: ChEBI [CHEBI:50266]  ( EBI )

Relationships
is a type of: drug pro-agent
inverse has_role: 2-hydroxy-17beta-estradiol 3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate 4-phenylbutyric acid 5-aminolevulinic acid 5-aminolevulinic acid hydrochloride abiraterone acetate acemetacin adefovir pivoxil alpha-N-dichloroacetyl-p-aminophenylserinol amifostine amodiaquine ampiroxicam amrubicin ancitabine aripiprazole lauroxil azaribine azathioprine azilsartan kamedoxomil azilsartan medoxomil AZT-1152 bacampicillin baicalin balsalazide bambuterol bambuterol hydrochloride beclomethasone dipropionate bempedoic acid benazepril bitolterol brivanib alaninate butane-1,4-diol cabozantinib malate capecitabine carbimazole cefamandole nafate cefditoren pivoxil cefotiam hexetil dihydrochloride cefotiam hexetil ester cefpodoxime proxetil ceftaroline fosamil ceftaroline fosamil acetate ceftaroline fosamil acetate monohydrate ceftobiprole medocaril CGP 78608 hydrochloride cilazapril cilazapril monohydrate clorazepate monopotassium clorazepic acid codeine colistimethate colistimethate sodium dabigatran etexilate dabigatran etexilate methanesulfonate dacarbazine dextilidine dextromethorphan diloxanide furoate dipivefrin dipotassium clorazepate dirithromycin doxifluridine droxicam droxidopa enalapril enalapril maleate etanidazole ethionamide ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate evofosfamide famciclovir fingolimod fingolimod hydrochloride flucytosine fludarabine phosphate fluphenazine decanoate fluticasone furoate fosamprenavir fosaprepitant fosaprepitant dimeglumine foscarbidopa Fosfluconazole fosinopril fosinopril sodium foslevodopa gabapentin enacarbil gemcitabine GSK-J4 heroin HMN-214 imidapril irinotecan irinotecan hydrochloride (anhydrous) irinotecan hydrochloride hydrate isavuconazonium isavuconazonium sulfate isopropyl unoprostone ixazomib citrate JHU083 JTE-607 dihydrochloride JTE-607 free base L-dopa lamivudine latanoprost leflunomide lefradafiban lenampicillin levomethorphan lovastatin loxoprofen lucanthone mestranol metamizole metamizole sodium methyl 5-aminolevulinate methyl 5-aminolevulinate hydrochloride methylprednisolone suleptanate metronidazole metronidazole benzoate metronidazole hydrochloride midodrine ML-210 molnupiravir mycophenolate mofetil myrophine N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide N-methylquipazine dimaleate nabumetone naproxcinod nelarabine nepafenac nitroglycerin nitrosulindac O-formylcefamandole olsalazine olsalazine sodium oseltamivir PABA/NO parecoxib pasireotide aspartate penamecillin PF-07304814 pivampicillin pivmecillinam prasugrel prednisolone phosphate prednisolone sodium phosphate prednisone proglumetacin proINDY psilocybin psilocybin(1-) pyrazinecarboxamide quinapril ramipril remdesivir rilpivirine hydrochloride roducitabine rolitetracycline rubitecan salicin salsalate sapacitabine SB 224289 hydrochloride selexipag simvastatin sodium phenylbutyrate sofosbuvir soyasaponin III spirapril sulbactam pivoxil sulfanegen sulindac suxibuzone talampicillin tazarotene tedizolid phosphate temozolomide tenofovir alafenamide tenofovir alafenamide fumarate tenofovir disoproxil tenofovir disoproxil fumarate tiazofurine tilidine trandolapril travoprost tributyrin uracil uridine triacetate valganciclovir varespladib methyl ximelagatran zofenopril zofenopril calcium