Term Name: E3040
Synonyms: 5,7-dimethyl-2-(methylamino)-4-(pyridin-3-ylmethyl)-1,3-benzothiazol-6-ol, 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole, E-3040, E3040
Definition: A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a methylnitrilo group, (pyridin-3-yl)methyl group, methyl group, hydroxy group and methyl group at position 2,4,5,6 and 7, respectively. It is a dual inhibitor of 5-lipoxygenase and thromboxane A2 synthetase and exhibits anti-inflammatory properties. The drug was being developed by Eisai (Tokyo, Japan) for the treatment of bowel disease.
Ontology: ChEBI [CHEBI:4732]  ( EBI )

Relationships
is a type of: benzothiazoles organic hydroxy compound pyridines secondary amino compound
has_role: anti-inflammatory drug EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor uricosuric drug
inverse has_functional_parent: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl hydrogen sulfate E3040 glucuronide