| Synonyms: |
(m-hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate),
3,3'-{decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide,
bromure de demecarium,
bromuro de demecario,
decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate)dimethobromide,
decamethylenebis(N-methylcarbamic acid m-dimethylaminophenyl ester) bromomethylate,
demecarii bromidum,
demecarium bromide,
N,N'-bis(3-trimethylammoniumphenoxycarbonyl)-N,N'-dimethyldecamethylenediamine dibromide
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| Definition: |
The methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure. |