Term Name: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
Synonyms: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitor, (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase inhibitors, (PG)H synthase inhibitor, (PG)H synthase inhibitors, COX inhibitor, cyclooxygenase (EC 1.14.99.1) inhibitor, cyclooxygenase (EC 1.14.99.1) inhibitors, cyclooxygenase inhibitor, cyclooxygenase inhibitors, EC 1.14.99.1 (cyclooxygenase) inhibitor, EC 1.14.99.1 (cyclooxygenase) inhibitors, EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitors, EC 1.14.99.1 inhibitor, EC 1.14.99.1 inhibitors, fatty acid cyclooxygenase inhibitor, fatty acid cyclooxygenase inhibitors, PG synthetase inhibitor, PG synthetase inhibitors, prostaglandin endoperoxide synthetase inhibitor, prostaglandin endoperoxide synthetase inhibitors, prostaglandin G/H synthase inhibitor, prostaglandin G/H synthase inhibitors, prostaglandin synthase inhibitor, prostaglandin synthase inhibitors, prostaglandin synthetase inhibitor, prostaglandin synthetase inhibitors
Definition: A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
Ontology: ChEBI [CHEBI:35544]  ( EBI )

Relationships
is a type of: EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor
has subtype: cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor cyclooxygenase 3 inhibitor
inverse has_role: (2S)-2-(4-{[(1R,2S)-2-hydroxycyclopentyl]methyl}phenyl)propanoic acid (6-methoxy-2-naphthyl)acetic acid 3',5'-di-O-methyltricetin 4-(methylamino)antipyrine 4-aminoantipyrine aceclofenac acemetacin aiphanol ampiroxicam carprofen clonixin clonixin lysine salt cudratricusxanthone A diclofenac flufenamic acid flunixin flunixin meglumine flurbiprofen ibufenac indometacin indoprofen ketoprofen licofelone lonazolac lonazolac calcium loxoprofen loxoprofen sodium loxoprofen sodium hydrate meclofenamic acid mefenamic acid naproxcinod nitrosulindac oxametacin piroxicam proglumetacin proglumetacin dimaleate PTUBP salicin sodium meclofenamate monohydrate sulindac suprofen tenidap tenoxicam tepoxalin tolfenamic acid tolmetin tolmetin sodium tolmetin sodium dihydrate vedaprofen