Term Name: compactin diol lactone
Synonyms: (4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}oxan-2-one, (4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}tetrahydro-2H-pyran-2-one, Antibiotic ML 236A, compactin diol lactone, desmethylmonacolin J, ML 236A, ML-236A
Definition: A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity.
Ontology: ChEBI [CHEBI:34652]  ( EBI )

Relationships
is a type of: 2-pyranones carbobicyclic compound hexahydronaphthalenes polyketide secondary alcohol
has_functional_parent: ML-236C
has_role: antiatherosclerotic agent anticholesteremic drug antilipemic drug antimicrobial agent EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor fungal metabolite