Term Name: butenafine
Synonyms: (4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine, (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, 1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, 4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine, butenafina, butenafine, butenafinum, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine
Definition: Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
Ontology: ChEBI [CHEBI:3238]  ( EBI )

Relationships
is a type of: naphthalenes tertiary amine
has_role: antifungal drug EC 1.14.13.132 (squalene monooxygenase) inhibitor
inverse has_part: butenafine hydrochloride