Term Name: | tibolone |
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Synonyms: | (17R)-17-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one, (7alpha,17alpha)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one, (7alpha,17beta)-17-ethynyl-17-hydroxy-7-methylestr-5(10)en-3-one, 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one, 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one, tibolona, tibolone, tibolonum |
Definition: | Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis. |
Ontology: | ChEBI [CHEBI:32223] ( EBI ) |