Term Name: aldosterone
Synonyms: (+)-aldosterone, (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al, 11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al, Aldosterone
Definition: A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
Ontology: ChEBI [CHEBI:27584]  ( EBI )

Relationships
is a type of: 3-oxo-Delta(4) steroid 11beta-hydroxy steroid 18-oxo steroid 20-oxo steroid 21-hydroxy steroid C21-steroid hormone mineralocorticoid primary alpha-hydroxy ketone steroid aldehyde
has_parent_hydride: pregnane
has_role: human metabolite mouse metabolite
inverse has_functional_parent: 5alpha-dihydroaldosterone 5beta-dihydroaldosterone aldosterone hemiacetal