Term Name: adefovir
Synonyms: 9-(2-(Phosphonomethoxy)ethyl)adenine, 9-(2-Phosphonylmethoxyethyl)adenine, Adefovir, DRG-0156, GS 0393, GS 393, GS-0393, HSDB 8079, N-(2-Phosphonylmethoxyethyl)adenine, PMEA, {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid
Definition: A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens has been replaced by a 2-(6-amino-9H-purin-9-yl)ethoxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(t-butoxycarbonyloxymethyl) ester (dipivoxil ester) prodrug is used to treat chronic hepatitis B viral infection.
Ontology: ChEBI [CHEBI:2469]  ( EBI )

Relationships
is a type of: 6-aminopurines ether phosphonic acids
has_functional_parent: adenine
has_role: antiviral drug DNA synthesis inhibitor drug metabolite HIV-1 reverse transcriptase inhibitor nephrotoxic agent
inverse has_functional_parent: adefovir pivoxil
inverse is_conjugate_base_of: adefovir(1-)
is_conjugate_acid_of: adefovir(1-)