Term Name: icosanoid
Synonyms: eicosanoid, eicosanoids, icosanoid, icosanoids
Definition: Any member of the group of signalling molecules arising from oxidation of the three C20 essential fatty acids (EFAs) icosapentaenoic acid (EPA), arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA).
Ontology: ChEBI [CHEBI:23899]  ( EBI )

Relationships
is a type of: fatty acid derivative
has subtype: (+/-)11-HEDE (2R)-2-Hydroxy-3-(icosanoyloxy)propyl (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoate (5Z,9E,12S,14Z)-8,11,12,20-tetrahydroxyicosa-5,9,14-trienoic acid (6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosatetraenoic acid (6E,8Z,11Z,13E,15S)-15-hydroxy-5-oxoicosatetraenoic acid (6E,8Z,11Z,14Z,17Z)-5-oxoicosapentaenoic acid (7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid (15E,17E)-9,10,12,13-tetrahydroxyhenicosa-15,17-dienoic acid 5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid 5(S),6-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid 5,8,11-icosatriynoic acid 5,20-diHEPE 11R-HEDE 11S-HEDE 12-HPE(8,10,14)TrE 12-Keto-tetrahydro-LTB4 13,14-dihydro-15-oxolipoxin A4 13,14-dihydrolipoxin A4 14-carboxy-15,16,17,18,19,20-hexanor-leukotriene E3 15R-HEDE 16-carboxy-17,18,19,20-tetranor-leukotriene E3 16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 18-carboxy-19,20-dinor-leukotriene E4 Auricolic acid bis(hydroperoxy)icosatetraenoic acid CA-phytotoxin CDP-DG(20:2(11Z,14Z)/6 keto-PGF1alpha) CDP-DG(20:3(5Z,8Z,11Z)/PGE1) CDP-DG(20:4(5Z,8Z,11Z,14Z)/PGF2alpha) CDP-DG(22:3(10Z,13Z,16Z)/5-iso PGF2VI) CDP-DG(22:3(10Z,13Z,16Z)/PGE2) CDP-DG(PGE2/20:2(11Z,14Z)) CDP-DG(PGE2/20:3(5Z,8Z,11Z)) CDP-DG(PGE2/22:3(10Z,13Z,16Z)) CDP-DG(PGF1alpha/22:3(10Z,13Z,16Z)) CDP-DG(PGJ2/20:2(11Z,14Z)) DG(8:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) DG(13:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) DG(14:1n5/0:0/20:5n3) DG(15:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) DG(16:1n7/0:0/20:5n3) DG(18:1n7/0:0/20:5n3) DG(18:1n9/0:0/20:5n3) DG(18:2n6/0:0/20:4n3) DG(18:2n6/0:0/20:5n3) DG(18:3n3/0:0/20:4n3) DG(18:3n6/0:0/20:3n6) DG(18:3n6/0:0/20:4n3) DG(18:3n6/0:0/20:4n6) DG(19:0/20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/0:0) DG(20:2n6/0:0/18:4n3) DG(20:2n6/0:0/20:4n3) DG(20:2n6/0:0/20:4n6) DG(20:2n6/0:0/20:5n3) DG(20:3n6/0:0/18:3n3) DG(20:3n6/0:0/18:4n3) DG(20:3n6/0:0/20:4n3) DG(20:3n6/0:0/20:4n6) DG(20:3n9/0:0/18:3n3) DG(20:3n9/0:0/18:3n6) DG(20:3n9/0:0/18:4n3) DG(20:3n9/0:0/20:4n3) DG(20:3n9/0:0/20:4n6) DG(20:4n6/0:0/18:3n3) DG(20:5(7Z,9Z,11E,13E,17Z)-3OH(5,6,15)/12:0/0:0) DHET dihydroxyicosatetraenoic acid EET eoxin EpETE HETE HPETE hydroperoxy(epoxy)icosatrienoic acid hydroperoxy(hydroxy)icosapentaenoic acid hydroperoxy(hydroxy)icosatetraenoic acid Hydroperoxy-eicosadienoic acid hydroperoxyicosapentaenoic acid hydroperoxyicosatrienoic acid icosenoic acid isoprostane leukotriene levuglandin methyl 6-hydroperoxy-4,8,11,14,17-eicosapentaenoate methyl 8-hydroperoxy-5,9,11,14,17-eicosapentaenoate methyl 9-hydroperoxy-5,7,11,14,17-eicosapentaenoate Mycestericin A Myriocin-12-en nonclassic icosanoid PI(6 keto-PGF1alpha/20:2(11Z,14Z)) PI(20:2(11Z,14Z)/PGF2alpha) PI(20:3(5Z,8Z,11Z)/PGE1) PI(20:3(5Z,8Z,11Z)/PGF1alpha) PI(20:3(5Z,8Z,11Z)/PGF2alpha) PI(20:4(5Z,8Z,11Z,14Z)/PGJ2) PI(22:3(10Z,13Z,16Z)/PGE1) PI(22:3(10Z,13Z,16Z)/PGF1alpha) PI(22:3(10Z,13Z,16Z)/TXB2) PI(PGE2/20:4(5Z,8Z,11Z,14Z)) PI(PGE2/22:3(10Z,13Z,16Z)) PI(PGJ2/20:3(5Z,8Z,11Z)) PI(TXB2/22:3(10Z,13Z,16Z)) prostanoid
inverse is_conjugate_base_of: icosanoid anion
is_conjugate_acid_of: icosanoid anion