Term Name: | BI-4020 |
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Synonyms: | [10(10a)E,18R]-1,6,18-trimethyl-14-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-1H,17H-8,4-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-9(11H)-one, BI 4020, BI4020 |
Definition: | A macrocycle with formula C30H38N8O2. It is a potent inhibitor of triple mutant EGFR(del19 T790M C797S) variant and shows efficacy for regressing tumor xenografts in vivo. |
Ontology: | ChEBI [CHEBI:232716] ( EBI ) |