Term Name: | SSTC3 |
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Synonyms: | 4-[methyl-[4-(trifluoromethyl)phenyl]sulfamoyl]-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)benzamide, 4-{methyl[4-(trifluoromethyl)phenyl]sulfamoyl}-N-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]benzamide, SSTC 3, SSTC-3 |
Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-{methyl[4-(trifluoromethyl)phenyl]sulfamoyl}benzoic acid with the amino group of 4-(pyridin-2-yl)-1,3-thiazol-2-amine. It is a casein kinase 1alpha activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). |
Ontology: | ChEBI [CHEBI:232382] ( EBI ) |