Term Name: EVP4593
Synonyms: 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, 6-amino-4-(4-phenoxyphenylethylamino)quinazoline, 6-amino-4-[2-(4-phenoxyphenyl)ethylamino]quinazoline, AG-F-89549, CAY 10470, CAY-10470, CAY10470, EVP 4593, EVP-4593, N(4)-(4-phenoxyphenethyl)quinazoline-4,6-diamine, N(4)-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine, N(4)-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, QNZ
Definition: A member of the class of quinazolines that is quinazoline substituted by [2-(4-phenoxyphenyl)ethyl]amino and amino groups at positions 4 and 6, respectively. It is an inhibitor of NF-kappaB signal transduction pathway and exhibits protective effects in oncology, cardiovascular disease and parasite invasion.
Ontology: ChEBI [CHEBI:232358]  ( EBI )

Relationships
is a type of: aromatic ether benzenes primary amino compound quinazolines secondary amino compound
has_role: anti-inflammatory agent antineoplastic agent antiparasitic agent apoptosis inducer EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor NF-kappaB inhibitor