| Synonyms: |
(3R)-4-(2-{4-[1-(3-methoxy[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl]phenoxy}ethyl)-1,3-dimethylpiperazin-2-one,
(3R)-4-[2-[4-[1-(3-methoxy-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-4-piperidinyl]phenoxy]ethyl]-1,3-dimethyl-2-piperazinone,
AZD 5153,
AZD-5153
|
| Definition: |
A member of the class of triazolopyridazines that is [1,2,4]triazolo[4,3-b]pyridazine substituted by methoxy and 4-(4-{2-[(2R)-2,4-dimethyl-3-oxopiperazin-1-yl]ethoxy}phenyl)piperidin-1-yl groups at positions 3 and 6, respectively. It is an orally bioavailable bivalent inhibitor of bromodomain-containing protein 4 with potential antineoplastic activity. |