Term Name: PF-06409577
Synonyms: 6-chloro-5-(4-(1-hydroxycyclobutyl)phenyl)-1H-indole-3-carboxylic acid, 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid, PF 06409577, PF06409577
Definition: A chloroindole that is 6-chloro-1H-indole substituted by carboxy and 4-(1-hydroxycyclobutyl)phenyl groups at positions 3 and 5, respectively. It is a potent and selective allosteric activator of AMPK and a potential treatment for diabetic nephropathy.
Ontology: ChEBI [CHEBI:231658]  ( EBI )

Relationships
is a type of: benzenes chloroindole cyclobutanes indolecarboxylic acid tertiary alcohol
has_role: antiatherosclerotic agent antineoplastic agent EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator nephroprotective agent