Term Name: iptacopan
Synonyms: 4-{(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl}benzoic acid, iptacopan, iptacopanum, LNP 023, LNP-023, LNP023, NVP-LNP023
Definition: A member of the class of indoles that is 1H-indole substituted by [(2S,4S)-2-(4-carboxyphenyl)-4-ethoxypiperidin-1-yl]methyl, methoxy, and methyl groups at positions 4, 5, and 6, respectively. It is a potent inhibitor of complement factor B (IC50 = 10nM) with potential immunomodulatory activity.
Ontology: ChEBI [CHEBI:229652]  ( EBI )

Relationships
is a type of: benzoic acids diether ether indoles monocarboxylic acid piperidines tertiary amino compound
has_role: complement factor B inhibitor immunomodulator
inverse is_conjugate_acid_of: iptacopan(1+)
is_conjugate_base_of: iptacopan(1+)