Term Name: fruquintinib
Synonyms: 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide, fruquintinib, fruquintinibum, Fruzaqla, HMPL-013
Definition: A member of the class of quinazolines that is quinazoline substituted by [2-methyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]oxy, methoxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a highly potent and selective inhibitor of VEGFR 1, 2 and 3 (IC50 = 33, 0.35, and 35 nM) used for the treatment of metastatic colorectal cancer.
Ontology: ChEBI [CHEBI:229221]  ( EBI )

Relationships
is a type of: 1-benzofurans aromatic ether quinazolines secondary carboxamide
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor vascular endothelial growth factor receptor antagonist