Term Name: repotrectinib
Synonyms: (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one, Augtyro, repotrectinib, repotrectinibum, TPX 0005, TPX-0005, TPX0005
Definition: An azamacrocycle with formula C18H18FN5O2. It is a tyrosine kinase inhibitor (highly potent against ROS1, TRKA-C, and ALK) used for the treatment of locally advanced or metastatic ROS1-positive non-small cell lung cancer.
Ontology: ChEBI [CHEBI:229220]  ( EBI )

Relationships
is a type of: azamacrocycle cyclic ether monofluorobenzenes pyrazolopyrimidine secondary carboxamide
has_role: antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor