Term Name: | KRIBB11 |
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Synonyms: | N(2)-(1H-indazol-5-yl)-N(6)-methyl-3-nitropyridine-2,6-diamine, N(2)-1H-indazol-5-yl-N(6)-methyl-3-nitro-2,6-pyridinediamine |
Definition: | A member of the class of indazoles that is 1H-indazole substituted by a [6-(methylamino)-3-nitropyridin-2-yl]amino group at position 5. It is an inhibitor of heat shock factor 1 (IC50 = 1.2muM) and suppresses tumour growth in mouse xenograft models. |
Ontology: | ChEBI [CHEBI:228800] ( EBI ) |