Term Name: KU-60019
Synonyms: 2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-{5-[6-(morpholin-4-yl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl}acetamide, KU 60019, KU60019
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of [(2R,6S)-2,6-dimethylmorpholin-4-yl]acetic acid with the amino group of 2-(7-amino-9H-thioxanthen-4-yl)-6-(morpholin-4-yl)-4H-pyran-4-one. It is an ATM kinase inhibitor (IC50 = 6.3 nM).
Ontology: ChEBI [CHEBI:228206]  ( EBI )

Relationships
is a type of: 4-pyranones morpholines secondary carboxamide tertiary amino compound thioxanthenes
has_role: antineoplastic agent autophagy inducer EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor radiosensitizing agent