Term Name: | AOH1996 |
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Synonyms: | AOH 1996, AOH-1996, N-{2-[2-(3-methoxyphenoxy)anilino]-2-oxoethyl}naphthalene-1-carboxamide |
Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of N-(naphthalen-1-ylcarbonyl)glycine with the amino group of 2-(3-methoxyphenoxy)aniline. It is a first-in-class small molecule inhibitor of PCNA, a protein essential for DNA replication and repair within tumours. |
Ontology: | ChEBI [CHEBI:195529] ( EBI ) |