Term Name: XL413
Synonyms: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, BMS 863233, BMS-863233, BMS863233, XL 413, XL-413
Definition: A benzofuropyrimidine that is 3,4-dihydro[1]benzofuro[3,2-d]pyrimidine substituted by (2S)-pyrrolidin-2-yl, oxo and chloro groups at positions 2, 4, and 8, respectively. It is a potent ATP competitive inhibitor of Cdc7 kinase (IC50 = 3.4 nM) and exhibits anticancer properties.
Ontology: ChEBI [CHEBI:189662]  ( EBI )

Relationships
is a type of: benzofuropyrimidine organochlorine compound pyrrolidines
has_role: antineoplastic agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor