Term Name: AR-42
Synonyms: (S)-HDAC 42, (S)-HDAC-42, AR 42, AR42, HDAC-42, N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide, N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide, OSU-HDAC42, REC 2282, REC-2282, REC2282
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-3-methyl-2-phenylbutanoic acid with the amino group of 4-amino-N-hydroxybenzamide. It is a pan-HDAC inhibitor that was in clinical development for the treatment of hematological malignancies and solid tumours.
Ontology: ChEBI [CHEBI:188197]  ( EBI )

Relationships
is a type of: benzenes hydroxamic acid secondary carboxamide
has_role: angiogenesis inhibitor antineoplastic agent apoptosis inducer EC 3.5.1.98 (histone deacetylase) inhibitor