Term Name: | molnupiravir |
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Synonyms: | beta-D-N(4)-hydroxycytidine-5'-isopropyl ester, EIDD 1931 5'-isopropylester, EIDD 2801, EIDD-2801, MK-4482, molnupiravir, molnupiravirum, N(4)-hydroxycytidine 5'-isopropylester, N-hydroxy-5'-O-(2-methylpropanoyl)-3,4-dihydrocytidine, {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]tetrahydrofuran-2-yl}methyl 2-methylpropanoate |
Definition: | A nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19. |
Ontology: | ChEBI [CHEBI:180653] ( EBI ) |