Term Name:	niraparib
Synonyms:	2-[4-(3S)-3-piperidinylphenyl]-2H-indazole-7-carboxamide, 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, MK 4827, MK-4827, MK4827, niraparib, niraparibum, Zejula
Definition:	A 2-[4-(piperidin-3-yl)phenyl]-2H-indazole-7-carboxamide that has S-configuration. It is a potent inhibitor of PARP1 and PARP2 (IC50 of 3.8 and 2.1 nM, respectively) and approved as a first-line maintenance treatment for women with advanced ovarian cancer after responding to platinum-based chemotherapy.
Ontology:	ChEBI [CHEBI:176844]  ( EBI )