Term Name: ML-210
Synonyms: [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone, DPI10, ML 210, ML210, {4-[bis(4-chlorophenyl)methyl]piperazin-1-yl}(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
Definition: An N-acylpiperazine that is piperazine substituted by 5-methyl-4-nitro-1,2-oxazole-3-carbonyl and bis(4-chlorophenyl)methyl groups at positions 1 and 4, respectively. It is a glutathione peroxidase 4 (GPX4) inhibitor which induces ferroptosis in cancer cells expressing the RAS oncogene.
Ontology: ChEBI [CHEBI:176502]  ( EBI )

Relationships
is a type of: C-nitro compound diarylmethane isoxazoles monochlorobenzenes N-acylpiperazine N-alkylpiperazine tertiary carboxamide
has_role: antineoplastic agent EC 1.11.1.9 (glutathione peroxidase) inhibitor ferroptosis inducer prodrug