Term Name: GSK2879552
Synonyms: 4-{[4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin-1-yl]methyl}benzoic acid, GSK 2879552, GSK-2879552
Definition: A member of the class of piperidines that is piperidine substituted by (4-carboxyphenyl)methyl and {[(1R,2S)-2-phenylcyclopropyl]amino}methyl groups at positions 1 and 4, respectively. It is a potent and irreversible inhibitor of lysine specific demethylase 1 (LSD1, also known as KDM1A). It was under clinical investigation for the treatment of acute myeloid leukaemia and small cell lung carcinoma.
Ontology: ChEBI [CHEBI:176334]  ( EBI )

Relationships
is a type of: benzenes benzoic acids cyclopropanes monocarboxylic acid piperidines secondary amino compound tertiary amino compound
has_role: antineoplastic agent EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor