Term Name: MP-A08
Synonyms: 4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide, 4-methyl-N-{2-[(2-{[(4-methylphenyl)sulfonyl]amino}benzylidene)amino]phenyl}benzenesulfonamide, MP A08, MPA08
Definition: A sulfonamide that consists of two moieties of 4-methyl-N-phenylbenzenesulfonamide connected to each other at position 2 by an aldimine linker. It is a ATP-competitive inhibitor of sphingosine kinase that targets both SK1 and SK2 (Ki values of 27 muM and 6.9 muM, respectively) and exhibits anti-cancer properties.
Ontology: ChEBI [CHEBI:167665]  ( EBI )

Relationships
is a type of: aldimine sulfonamide toluenes
has_role: angiogenesis inhibitor antineoplastic agent apoptosis inducer EC 2.7.1.91 (sphingosine kinase) inhibitor