| Term Name: | MP-A08 |
|---|---|
| Synonyms: | 4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide, 4-methyl-N-{2-[(2-{[(4-methylphenyl)sulfonyl]amino}benzylidene)amino]phenyl}benzenesulfonamide, MP A08, MPA08 |
| Definition: | A sulfonamide that consists of two moieties of 4-methyl-N-phenylbenzenesulfonamide connected to each other at position 2 by an aldimine linker. It is a ATP-competitive inhibitor of sphingosine kinase that targets both SK1 and SK2 (Ki values of 27 μM and 6.9 μM, respectively) and exhibits anti-cancer properties. |
| Ontology: | ChEBI [CHEBI:167665] ( EBI ) |