Term Name: Glu-Gly-Arg-chloromethylketone
Synonyms: chloromethylketone-EGR, EGR-chloromethylketone, EGR-CMK, EGRCK, Glu-Gly-Arg-chloromethylketone, glutamyl-glycyl-arginine chloromethyl ketone, H-Glu-Gly-Arg-CH2Cl, H-Glu-Gly-Arg-chloromethylketone, L-alpha-glutamyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]glycinamide, L-Glu-Gly-L-Arg-chloromethylketone
Definition: A tripeptide composed of L-glutamic acid, glycine and L-arginine joined in sequence by peptide linkages and in which the carboxy terminus is substituted by a chloroacetyl group. It is a potent and irreversible inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa.
Ontology: ChEBI [CHEBI:157651]  ( EBI )

Relationships
is a type of: organochlorine compound tripeptide
has_functional_parent: glycine L-arginine L-glutamic acid
has_role: EC 3.4.21.6 (coagulation factor Xa) inhibitor