Term Name:	10058-F4
Synonyms:	10058F4, 5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one, 5-(4-ethylbenzylidene)-2-sulfanylidene-1,3-thiazolidin-4-one, 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one, 5-[(4-ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Definition:	A member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase.
Ontology:	ChEBI [CHEBI:149696]  ( EBI )