Term Name: | 6-de(cyclopropylamino)-6-(isopropylamino)abacavir |
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Synonyms: | (1S,4R)-4-[2-amino-6-[(1-methylethyl)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol, [(1S,4R)-4-{2-amino-6-[(propan-2-yl)amino]-9H-purin-9-yl}cyclopent-2-en-1-yl]methanol, {(1S,4R)-4-[2-amino-6-(isopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol |
Definition: | A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by a 3-isopropoxyazetidin-1-yl group. Unlike several other synthesised abacavir analogues, it is completely deficient in T-cell reactivity with abacavir-responsive clones. |
Ontology: | ChEBI [CHEBI:149439] ( EBI ) |