Term Name: | 6-de(cyclopropylamino)-6-(3-isopropoxyazetidin-1-yl)abacavir |
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Synonyms: | (1S,4R)-4-[2-amino-6-[3-(1-methylethoxy)-1-azetidinyl]-9H-purin-9-yl]-2-cyclopentene-1-methanol, [(1S,4R)-4-(2-amino-6-{3-[(propan-2-yl)oxy]azetidin-1-yl}-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol |
Definition: | A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by a 3-isopropoxyazetidin-1-yl group. One of a series of synthesised abacavir analogues with antiviral activity found to stimulate IFN-gamma secretion in abacavir-responsive clones. |
Ontology: | ChEBI [CHEBI:149432] ( EBI ) |