Term Name: VPC 23019
Synonyms: (2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate, (2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide, (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester, N-(3-octylphenyl)-O-phosphono-D-serinamide, VPC-23019, VPC23019
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.
Ontology: ChEBI [CHEBI:144948]  ( EBI )

Relationships
is a type of: aromatic amide D-serine derivative organic phosphate phosphoric ester secondary carboxamide
has_functional_parent: O-phospho-D-serine
has_role: sphingosine-1-phosphate receptor 1 antagonist sphingosine-1-phosphate receptor 3 antagonist