Term Name: | N-glycolylneuraminyllactosylceramide |
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Synonyms: | (2S,3R,4E)-3-hydroxy-2-(octadecanoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, (2S,3R,4E)-3-hydroxy-2-(stearoylamino)octadec-4-en-1-yl 3,5-dideoxy-5-(glycoloylamino)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, (5alpha,17alpha)-N-deacetyl-N-(hydroxyacetyl)-ganglioside GM3, 1-O-(O-(N-(hydroxyacetyl)-alpha-neuraminosyl)-(2-3)-O-beta-D-galactopyranosyl-(1-4)-beta-D-glucopyranosyl)-ceramide, GM3-Neugc, HD3 ganglioside, N-glycoloyl-GM3, N-glycolyl-neuraminyl-lactosyl-ceramide, Neugc(alpha2-3)gal(beta1-4)glc(beta1-1)cer, Neugc-GM3 |
Definition: | A sialotriaosylceramide in which the triaosyl group is 3,5-dideoxy-5-(2-hydroxyacetamido)-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl attached to the primary hydroxy function of ceramide. A tumour antigen found in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but not usually detected in normal human cells. |
Ontology: | ChEBI [CHEBI:144806] ( EBI ) |