Term Name: | 16,16-dimethylprostaglandin E2 |
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Synonyms: | (5Z,11alpha,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid, 16,16-dimethyl Prostaglandin E2, 16,16-Dimethyl-pge2, 16,16-Dimethyl-prostaglandin E2, 9-oxo-11R,15R-dihydroxy-16,16-dimethyl-5Z,13E-prostadienoic acid, dmPGE(2), dmPGE2 |
Definition: | A prostanoid that is prostaglandin E2 in which both of the hydrogens at position 16 have been replaced by methyl groups. A synthetic analogue of prostaglandin E2, it is a potent inhibitor of pancreatic function and growth of experimental tumors. It also protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. |
Ontology: | ChEBI [CHEBI:141046] ( EBI ) |