Term Name: golgicide A
Synonyms: 6,8-Difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline, GCA
Definition: A diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181).
Ontology: ChEBI [CHEBI:139037]  ( EBI )

Relationships
is a type of: diastereoisomeric mixture
has_part: cis-golgicide A trans-golgicide A
has_role: cis-Golgi ArfGEF GBF inhibitor