Term Name: (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane dihydrochloride
Synonyms: 4-methyl-5-[(2S)-2-methyl-1,4-diazepane-1-sulfonyl]isoquinoline dihydrochloride, dimethyl fasudil dihydrochloride, H-1152 dihydrochloride, ROCK inhibitor
Definition: A hydrochloride salt resulting from the reaction of (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane with 2 mol eq. of hydrogen chloride. An ATP-competitive inhibitor of Rho kinase (ROCK).
Ontology: ChEBI [CHEBI:137694]  ( EBI )

Relationships
is a type of: hydrochloride
has_part: (S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane(2+)
has_role: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor