Term Name: rhosin
Synonyms: (2R)-2-amino-3-(1H-indol-3-yl)-N'-[(E)-(quinoxalin-6-yl)methylidene]propanehydrazide, (quinoxalinylmethylidene-D-tryptophanyl)hydrazide, D-tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide, Rho Inhibitor
Definition: A D-tryptophan derivative obtained by formal condensation of the carboxy group of D-tryptophan with the amino group of (quinoxalin-6-yl)methylidenehydrazide. It directly targets the Rho GEF binding domain, thereby preventing Rho from interacting with its GEFs
Ontology: ChEBI [CHEBI:137693]  ( EBI )

Relationships
is a type of: D-tryptophan derivative hydrazone quinoxaline derivative
has_role: antineoplastic agent RhoA inhibitor RhoC inhibitor