Term Name: cycloguanil
Synonyms: 1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-triazine-2,4-diamine, 1-(p-chlorophenyl)-4,6-diamino-2,2-dimethyl-1,2-dihydro-s-triazine, Chlorcycloguanil
Definition: A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.
Ontology: ChEBI [CHEBI:135029]  ( EBI )

Relationships
is a type of: triazines
has_role: antifolate antiinfective agent antimalarial antiparasitic agent antiprotozoal drug EC 1.5.1.3 (dihydrofolate reductase) inhibitor
inverse has_part: cycloguanil hydrochloride