Term Name: RO4927350
Synonyms: (2S,3S)-2-{(4R)-4-[4-(2-hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl}-3-phenyl-N-(4-propionyl-1,3-thiazol-2-yl)butanamide, Ro 4927350, RO-4927350
Definition: A carboxamide resulting from the formal condensation of the primary amino group of 4-propanoyl-1,3-thiazol-2-amine with the carboxy group of a 3-phenylbutiyric acid which has been substituted at position 2 by a (4R)-4-[p-(2-hydroxyethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl group. It is a potent, highly selective inhibitormitogen-activated protein kinase 1/2 inhibitor.
Ontology: ChEBI [CHEBI:132984]  ( EBI )

Relationships
is a type of: 1,3-thiazoles aromatic ketone imidazolidine-2,4-dione secondary carboxamide
has_role: EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor