Term Name: | 680C91 |
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Synonyms: | 6-fluoro-3-[(E)-2-(pyridin-3-yl)vinyl]-1H-indole |
Definition: | A fluoroindole that is 6-fluoroindole in which the hydrogen at position 3 has been replaced by a 2-(pyridin-3-yl)vinyl group (trans configuration). It is a selective inhibitor of tryptophan 2,3-dioxygenase (TDO), which directs the conversion of trypophan to kynurenin. |
Ontology: | ChEBI [CHEBI:131851] ( EBI ) |