Term Name: Ro 5-3335
Synonyms: 7-chloro-5-(1H-pyrrol-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 7-chloro-5-(2-pyrryl)-3H-1,4-benzodiazepin-2(H)-one, CBFbeta-Runx1 inhibitor II, Ro-5-3335, Ro5-3335
Definition: A 1,4-benzodiazepinone that is nordazepam in which the phenyl substituent has been replaced by a 1H-pyrrol-2-yl group. It inhibits gene expression in HIV-1 at the transcriptional level through interference with Tat-mediated transactivation.
Ontology: ChEBI [CHEBI:131785]  ( EBI )

Relationships
is a type of: 1,4-benzodiazepinone organochlorine compound pyrroles
has_role: anti-HIV-1 agent antineoplastic agent HIV-1 Tat inhibitor RUNX1 inhibitor